.tb-container .tb-container-inner{width:100%;margin:0 auto} .wp-block-toolset-blocks-container.tb-container[data-toolset-blocks-container="8cfa9029d84d91f2d5f769e44930cd7b"] { padding: 0px 5px 0px 5px; } .tb-field[data-toolset-blocks-field="b81e298d6a608136c9d2bda25bd70437"] { font-size: 14px;font-weight: normal;line-height: 1.3em;color: rgba( 12, 18, 45, 1 ); }  .tb-field[data-toolset-blocks-field="480f8fec6a995870d84089a1ddef31c6"] { font-size: 16px;line-height: 1.3em; }   .tb-grid,.tb-grid>.block-editor-inner-blocks>.block-editor-block-list__layout{display:grid;grid-row-gap:25px;grid-column-gap:25px}.tb-grid-item{background:#d38a03;padding:30px}.tb-grid-column{flex-wrap:wrap}.tb-grid-column>*{width:100%}.tb-grid-column.tb-grid-align-top{width:100%;display:flex;align-content:flex-start}.tb-grid-column.tb-grid-align-center{width:100%;display:flex;align-content:center}.tb-grid-column.tb-grid-align-bottom{width:100%;display:flex;align-content:flex-end} .wpv-view-output[data-toolset-views-view-editor="1df507648ad383b8e9c27b0267d917a1"] > .tb-grid-column:nth-of-type(3n + 1) { grid-column: 1 } .wpv-view-output[data-toolset-views-view-editor="1df507648ad383b8e9c27b0267d917a1"] > .tb-grid-column:nth-of-type(3n + 2) { grid-column: 2 } .wpv-view-output[data-toolset-views-view-editor="1df507648ad383b8e9c27b0267d917a1"] > .tb-grid-column:nth-of-type(3n + 3) { grid-column: 3 } .wpv-view-output[data-toolset-views-view-editor="1df507648ad383b8e9c27b0267d917a1"] .js-wpv-loop-wrapper > .tb-grid { grid-template-columns: minmax(0, 0.3333fr) minmax(0, 0.3333fr) minmax(0, 0.3333fr);grid-auto-flow: row } .tb-container .tb-container-inner{width:100%;margin:0 auto} .wp-block-toolset-blocks-container.tb-container[data-toolset-blocks-container="4217b81dfacad8048c7cf0373583be1d"] { border-radius: 0 16px 16px 16px;background: rgba( 255, 255, 255, 1 );padding: 0px;margin: 0px 0px 10px 0px;box-shadow: 0 10px 100px 0 rgba( 27, 95, 193, 0.16 ); } .tb-grid,.tb-grid>.block-editor-inner-blocks>.block-editor-block-list__layout{display:grid;grid-row-gap:25px;grid-column-gap:25px}.tb-grid-item{background:#d38a03;padding:30px}.tb-grid-column{flex-wrap:wrap}.tb-grid-column>*{width:100%}.tb-grid-column.tb-grid-align-top{width:100%;display:flex;align-content:flex-start}.tb-grid-column.tb-grid-align-center{width:100%;display:flex;align-content:center}.tb-grid-column.tb-grid-align-bottom{width:100%;display:flex;align-content:flex-end} .wp-block-toolset-blocks-grid.tb-grid[data-toolset-blocks-grid="3cdccdf097e1f2015cd57678a71e3660"] { padding-top: 15px;padding-bottom: 15px;margin-right: 1.5em;margin-left: 1.5em;grid-template-columns: minmax(0, 0.055fr) minmax(0, 0.945fr);grid-column-gap: 15px;grid-row-gap: 10px;grid-auto-flow: row } .wp-block-toolset-blocks-grid.tb-grid[data-toolset-blocks-grid="3cdccdf097e1f2015cd57678a71e3660"] > .tb-grid-column:nth-of-type(2n + 1) { grid-column: 1 } .wp-block-toolset-blocks-grid.tb-grid[data-toolset-blocks-grid="3cdccdf097e1f2015cd57678a71e3660"] > .tb-grid-column:nth-of-type(2n + 2) { grid-column: 2 } .wp-block-toolset-blocks-grid-column.tb-grid-column[data-toolset-blocks-grid-column="d586521f59ec8ce1ef613d87411ef3fd"] { padding-top: 10px;padding-bottom: 10px;display: flex; } h3.tb-heading[data-toolset-blocks-heading="d7bf812ac5da37d1fb2f5ef00b2dd30b"]  { font-size: 20px;line-height: 1.3em; }  .wp-block-toolset-blocks-grid-column.tb-grid-column[data-toolset-blocks-grid-column="83a72456e82f8d3034dc319f7a516ab9"] { padding: 8px 0px 0px 0px;margin-top: 0px;margin-bottom: 0px;margin-left: 0px;display: flex; } @media only screen and (max-width: 781px) { .tb-container .tb-container-inner{width:100%;margin:0 auto} .wp-block-toolset-blocks-container.tb-container[data-toolset-blocks-container="8cfa9029d84d91f2d5f769e44930cd7b"] { margin-right: 5px;margin-left: 5px; }    .tb-grid,.tb-grid>.block-editor-inner-blocks>.block-editor-block-list__layout{display:grid;grid-row-gap:25px;grid-column-gap:25px}.tb-grid-item{background:#d38a03;padding:30px}.tb-grid-column{flex-wrap:wrap}.tb-grid-column>*{width:100%}.tb-grid-column.tb-grid-align-top{width:100%;display:flex;align-content:flex-start}.tb-grid-column.tb-grid-align-center{width:100%;display:flex;align-content:center}.tb-grid-column.tb-grid-align-bottom{width:100%;display:flex;align-content:flex-end} .wpv-view-output[data-toolset-views-view-editor="1df507648ad383b8e9c27b0267d917a1"] > .tb-grid-column:nth-of-type(3n + 1) { grid-column: 1 } .wpv-view-output[data-toolset-views-view-editor="1df507648ad383b8e9c27b0267d917a1"] > .tb-grid-column:nth-of-type(3n + 2) { grid-column: 2 } .wpv-view-output[data-toolset-views-view-editor="1df507648ad383b8e9c27b0267d917a1"] > .tb-grid-column:nth-of-type(3n + 3) { grid-column: 3 } .wpv-view-output[data-toolset-views-view-editor="1df507648ad383b8e9c27b0267d917a1"] .js-wpv-loop-wrapper > .tb-grid { grid-template-columns: minmax(0, 0.3333fr) minmax(0, 0.3333fr) minmax(0, 0.3333fr);grid-auto-flow: row } .tb-container .tb-container-inner{width:100%;margin:0 auto} .wp-block-toolset-blocks-container.tb-container[data-toolset-blocks-container="4217b81dfacad8048c7cf0373583be1d"] { margin-right: 0px;margin-left: 0px; } .tb-grid,.tb-grid>.block-editor-inner-blocks>.block-editor-block-list__layout{display:grid;grid-row-gap:25px;grid-column-gap:25px}.tb-grid-item{background:#d38a03;padding:30px}.tb-grid-column{flex-wrap:wrap}.tb-grid-column>*{width:100%}.tb-grid-column.tb-grid-align-top{width:100%;display:flex;align-content:flex-start}.tb-grid-column.tb-grid-align-center{width:100%;display:flex;align-content:center}.tb-grid-column.tb-grid-align-bottom{width:100%;display:flex;align-content:flex-end} .wp-block-toolset-blocks-grid.tb-grid[data-toolset-blocks-grid="3cdccdf097e1f2015cd57678a71e3660"] { grid-template-columns: minmax(0, 0.5fr) minmax(0, 0.5fr);grid-auto-flow: row } .wp-block-toolset-blocks-grid.tb-grid[data-toolset-blocks-grid="3cdccdf097e1f2015cd57678a71e3660"] > .tb-grid-column:nth-of-type(2n + 1) { grid-column: 1 } .wp-block-toolset-blocks-grid.tb-grid[data-toolset-blocks-grid="3cdccdf097e1f2015cd57678a71e3660"] > .tb-grid-column:nth-of-type(2n + 2) { grid-column: 2 } .wp-block-toolset-blocks-grid-column.tb-grid-column[data-toolset-blocks-grid-column="d586521f59ec8ce1ef613d87411ef3fd"] { display: flex; } h3.tb-heading[data-toolset-blocks-heading="d7bf812ac5da37d1fb2f5ef00b2dd30b"]  { line-height: 1.3em; }  .wp-block-toolset-blocks-grid-column.tb-grid-column[data-toolset-blocks-grid-column="83a72456e82f8d3034dc319f7a516ab9"] { display: flex; }  } @media only screen and (max-width: 599px) { .tb-container .tb-container-inner{width:100%;margin:0 auto} .wp-block-toolset-blocks-container.tb-container[data-toolset-blocks-container="8cfa9029d84d91f2d5f769e44930cd7b"] { margin-right: 0px;margin-left: 0px; }    .tb-grid,.tb-grid>.block-editor-inner-blocks>.block-editor-block-list__layout{display:grid;grid-row-gap:25px;grid-column-gap:25px}.tb-grid-item{background:#d38a03;padding:30px}.tb-grid-column{flex-wrap:wrap}.tb-grid-column>*{width:100%}.tb-grid-column.tb-grid-align-top{width:100%;display:flex;align-content:flex-start}.tb-grid-column.tb-grid-align-center{width:100%;display:flex;align-content:center}.tb-grid-column.tb-grid-align-bottom{width:100%;display:flex;align-content:flex-end} .wpv-view-output[data-toolset-views-view-editor="1df507648ad383b8e9c27b0267d917a1"]  > .tb-grid-column:nth-of-type(1n+1) { grid-column: 1 } .wpv-view-output[data-toolset-views-view-editor="1df507648ad383b8e9c27b0267d917a1"] .js-wpv-loop-wrapper > .tb-grid { grid-template-columns: minmax(0, 1fr);grid-auto-flow: row } .tb-container .tb-container-inner{width:100%;margin:0 auto} .wp-block-toolset-blocks-container.tb-container[data-toolset-blocks-container="4217b81dfacad8048c7cf0373583be1d"] { margin-right: 0px;margin-left: 0px; } .tb-grid,.tb-grid>.block-editor-inner-blocks>.block-editor-block-list__layout{display:grid;grid-row-gap:25px;grid-column-gap:25px}.tb-grid-item{background:#d38a03;padding:30px}.tb-grid-column{flex-wrap:wrap}.tb-grid-column>*{width:100%}.tb-grid-column.tb-grid-align-top{width:100%;display:flex;align-content:flex-start}.tb-grid-column.tb-grid-align-center{width:100%;display:flex;align-content:center}.tb-grid-column.tb-grid-align-bottom{width:100%;display:flex;align-content:flex-end} .wp-block-toolset-blocks-grid.tb-grid[data-toolset-blocks-grid="3cdccdf097e1f2015cd57678a71e3660"] { grid-template-columns: minmax(0, 1fr);grid-auto-flow: row } .wp-block-toolset-blocks-grid.tb-grid[data-toolset-blocks-grid="3cdccdf097e1f2015cd57678a71e3660"]  > .tb-grid-column:nth-of-type(1n+1) { grid-column: 1 } .wp-block-toolset-blocks-grid-column.tb-grid-column[data-toolset-blocks-grid-column="d586521f59ec8ce1ef613d87411ef3fd"] { margin-top: -10px;display: flex; }  .wp-block-toolset-blocks-grid-column.tb-grid-column[data-toolset-blocks-grid-column="83a72456e82f8d3034dc319f7a516ab9"] { display: flex; }  } 

MetabERN Italy

MetabERN Italy is the first MetabERN national hub, a pilot project which was established in 2022. The creation of MetabERN Italy paved the way for other European countries to associate and develop national hubs themselves. These hubs could benefit both countries with a high number of centres (such as Spain, Germany, France and Portugal) and small countries that share similar features.

The establishment of national hubs, strongly endorsed by the European Commission, aims to pursue the following goals:

cluster national initiatives
provide a central point of contact in each country, ensuring better national coordination
decentralise ERNs to improve accessibility for patients
facilitate the integration of ERNs into the National Healthcare Systems
promote education and awareness initiatives at a national level
identify differences between Member States and collect input on national priorities
consolidate regional expert communities in specific domains

Distribution

Half of the Italian regions are covered by MetabERN, having at least one representative HCP within their territory. Italy has 18 healthcare providers involved in MetabERN, which are spread across 10 regions.

Here you can find the list of the HCP that belong to our national hub. Have a look at the map below to see how we are distributed in our country!

Please tap icons on the map to see health care center’s information.

Please click icons on the map to see health care center’s information.

University Hospital Policlinico G.Rodolico-San Marco

HCP Representative: Agata Fiumara

Foundation IRCCS CA’Granda Ospedale Maggiore polyclinic – Milan

HCP Representative: Francesca Menni

Foundation polyclinic University A. Gemelli – Rome

HCP Representative: Raffaele Manna

AO City of Health and Science – Turin

HCP Representative: Marco Spada

IRCCS AOU Policlinico “S.Orsola-Malpighi”

HCP Representative: Andrea Pession

AOU University of Campania “Luigi Vanvitelli”

HCP Representative: Marina Melone

AOU Policlinico Umberto I – Rome

HCP Representative: Vincenzo Leuzzi

AOU Pisana

Obesity Center endocrnolgy Unit, Pisa

HCP Representative: Ferruccio Santini

AOU Meyer – Florence

Metabolic, muscular, newborn screening Clinical Unit, Florence

HCP Representative: Maria Alice Donati

Hospital San Paolo – Milan

DPT of Health Sciences – University of Milan

HCP Representative: Graziella Cefalo

AOU Siena

HCP Representative: Bruno Frediani

University Hospital of Padova

Division of Inherited Metabolic Diseases

HCP Representative: Alberto Burlina

AOU of Udine

Centre for Rare Diseases, Udine

HCP Representative: Maurizio Scarpa

S. Gerardo Hospital – Monza

Center for rare Diseases, Monza

HCP Representative: Serena Gasperini

AOU Federico II – Naples

HCP Representative: Giancarlo Parenti

IRCCS Institute Giannina Gaslini – Genoa

Unit of rare Diseases

HCP Representative: Maria Cristina Schiaffino

AOUI Verona

Regional Centre for Newborn Screening, Diagnosis and Treatment of Inherited Metabolic Disorders, Department of Pediatrics

HCP Representative: Domenico Girelli

Pediatric Hospital Bambino Gesù

HCP Representative: Carlo Dionisi Vici

Aims and activities

Our national hub consists of healthcare professionals, patient representatives, and experts working together to provide high-quality care and support to patients across Italy.

Our objectives at MetabERN Italy are interconnected with the objectives of the European Network, all aimed at improving the lives of those affected by rare hereditary metabolic disorders. Here you can take a look at what we are doing and what we want to achieve:

we are collaborating with regional registries and the national registry at CNMR (National Centre for Rare Diseases) to ensure that accurate data is collected and used to improve patient outcomes. We also want to increase the number of Italian MetabERN centres registered in the U-IMD.
we are creating and updating Diagnostic and Therapeutic Care Pathways (Percorsi Diagnostico Terapeutici e Assistenziali, PDTA)that will guide healthcare professionals in the diagnosis, treatment, and management of rare metabolic disorders, ensuring standardised and optimal care for patients.
we want to make the Italian system of newborn screening (NBS) an example for other Member States, ensuring that all newborns are screened for metabolic disorders and receive timely interventions.
We are utilising the CPMS platform to speed up the diagnosis and counseling of selected clinical cases, facilitating collaboration between healthcare professionals.
We are committed to support patients in their transition from paediatric to adult healthcare, creating a national program and guidelines to ensure a smooth and consistent transition process for adolescents with IMDs.
We believe that education is a key aspect and we want to ensure that healthcare professionals are equipped with the knowledge and skills to provide the best possible care for patients.
we are coordinating research efforts in a structured way, extending collaborations to preclinical institutes to advance our understanding of IMDs

We are also aimed to be the referral advisory body for several institutions:

Istituto Superiore di Sanità – ISS (The Italian National Institute of Health)
The Ministry of Health,
The Regional Health Authorities,
SIMMESN and possibly other Scientific Societies and Organisations
Local health agencies and hospitals.
UNIAMO and other patient associations
Industry and other relevant stakeholders

Coordination team

MetabERN Italy was initially led by Carlo Dionisi-Vici, paediatrician and Head of the Unit of Metabolic Disease at the Bambino Gesù Children’s Research Hospital in Rome and is currently lead by Serena Gasperini (Fondazione IRCCS San Gerardo dei Tintori, Monza). The coordination team is also composed of Maria Letizia Urban (IRCCS Meyer – Azienda Ospedaliera Universitaria, Firenze) and Giacomo Marchi (Azienda Ospedaliera Universitaria Integrata Verona), representing the adult patient area, and Diego Martinelli (Ospedale Pediatrico Bambino Gesù, Roma) and Annalisa Madeo (IRCCS Istituto Giannina Gaslini, Genova) for the paediatric patient area.