This module deals with trace elements and vitamins metabolism. Specifically, Wilson disease is presented as an example of a disorder affecting the cupper metabolism. The accumulation of cupper due to a defective elimination from the liver into the bile gives rise to chronic liver disease (liver cirrhosis), hemolysis and neurological symptoms. Several treatment options for Wilson disease are discussed. Hyperhomocysteinemia can have different clinical presentations and can be caused by different metabolic defects: primary enzymatic deficiencies or disturbances in cofactors, as vitamin B12 and folic acid. In this module, also the importance of vitamins in the treatment of inherited metabolic diseases are put forward.
Authors: David Cassiman, François Eyskens, Viktor Kozich
The Diagnostic, Clinical and Therapeutic Education Programme on Inherited Metabolic Disorders. Module 11: Trace elements & vitamins made available on https://metab.ern-net.eu/education-programme/ and organized by MetabERN – European Reference Network for Hereditary Metabolic Disorders is accredited by the European Accreditation Council for Continuing Medical Education (EACCME®) to provide the following CME activity for medical specialists. Only those e-learning materials that are displayed on the UEMS-EACCME® website have formally been accredited.
Only those e-learning materials that are displayed on the UEMS-EACCME® website have formally been accredited.
Through an agreement between the European Union of Medical Specialists and the American Medical Association, physicians may convert EACCME® credits to an equivalent number of AMA PRA Category 1 Credits™. Information on the process to convert EACCME® credits to AMA credits can be found at https://edhub.ama-assn.org/pages/applications.
This Module has been awarded with 1 ECMEC® credit
