2.1.f

Disorders of sphingolipid synthesis and recycling

  • Serine palmitoyltransferase subunit 1 deficiency (Hereditary sensory and autonomic neuropathy type 1A)
  • Serine palmitoyltransferase subunit 2 deficiency (Hereditary sensory and autonomic neuropathy type 1C)
  • 3-Ketodihydrosphingosine reductase deficiency (Erythrokeratodermia variabilis et progressiva type 4)
  • Ceramide synthase 1 deficiency (Progressive myoclonic epilepsy type 8)
  • Ceramide synthase 2 deficiency
  • Ceramide synthase 3 deficiency (Autosomal recessive congenital ichthyosis type 9)
  • Dihydroceramide desaturase deficiency
  • Alkaline ceramidase 3 deficiency (Early childhood-onset progressive leukodystrophy)
  • CYP4F22 omega hydroxylase deficiency (Autosomal recessive congenital ichthyosis type 5)
  • Fatty acid transport protein 4 deficiency (Ichthyosis prematurity syndrome)
  • Acylceramide transacylase deficiency (Autosomal recessive congenital ichthyosis type 1)
  • UDP-glucose ceramide glucosyltransferase deficiency (Autosomal recessive congenital ichthyosis)
  • ABCA12 lipid transporter deficiency (Autosomal recessive congenital ichthyosis type 4)
  • Arachidonate 12-lipoxygenase, R type deficiency (Autosomal recessive congenital ichthyosis type 2)
  • Arachidonate lipoxygenase 3 deficiency (Autosomal recessive congenital ichthyosis type 3)
  • SDR9C7 deficiency (Autosomal recessive congenital ichthyosis type 13)
  • Nonlysosomal glucosylceramidase deficiency (Autosomal recessive spastic paraplegia type 46)
  • Fatty acid 2-hydroxylase deficiency (Autosomal recessive spastic paraplegia type 35; fatty acid hydroxylase-associated neurodegeneration – FAHN)
  • Sphingosine-1-phosphate lyase deficiency
  • Sphingosine-1-phosphate transporter deficiency
  • Sphingomyelin synthase 2 deficiency (Osteoporosis with calvarial doughnut lesions)

Subnetworks

PD 1 1

PD

Peroxisomal and lipid-related disorders

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